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目的观察妊娠中晚期孕妇肝内胆汁淤积症(ICP)的治疗效果,探讨其临床应用价值。方法选取2010年9月至2011年8月在我院产科住院的肝内胆汁淤积症孕妇共84例,随机分为对照组与观察组,每组各42例,其中对照组孕妇给予地塞米松静脉滴注,观察组孕妇在此基础上加用茵栀黄颗粒,观察并比较两组患者临床疗效。结果观察组临床总有效40例,总有效率为95.23%,明显高于对照组(80.95%),两组比较差异具有统计学意义(P<0.05)。结论中西医结合治疗妊娠中晚期肝内胆汁淤积症效果显著,对胎儿或孕妇影响较小,安全性好,值得临床推广和应用。
Objective To observe the therapeutic effect of intrahepatic cholestasis (ICP) in pregnant women in the second and third trimester of pregnancy and to explore its clinical value. Methods A total of 84 pregnant women with intrahepatic cholestasis hospitalized in our hospital from September 2010 to August 2011 were randomly divided into control group and observation group with 42 cases in each group. Pregnant women in the control group were given dexamethasone Intravenous drip, observation group pregnant women on this basis with Yinzhihuang granules, observe and compare the clinical efficacy of two groups of patients. Results The total effective rate of observation group was 40 cases, the total effective rate was 95.23%, which was significantly higher than that of the control group (80.95%). There was significant difference between the two groups (P <0.05). Conclusion Integrative Chinese and Western medicine treatment of intrahepatic cholestasis of pregnancy has a significant effect on the fetus or pregnant women less affected, good safety, worthy of clinical promotion and application.