一、糖皮质激素(GC)药物及其在机体内的动态皮质素在体内变换为皮质醇才能发挥作用。呼吸疾病应用GC并非像肾上腺皮质低功时以补偿皮质醇的疗法,而是以GC的抗炎作用或者是以其免疫抑制作用,以期达到治疗目的。因此,需要更强的抗炎作用的GC和防止其副作用,特别是减少由皮质素引起的电解质变化。至今已开发了许多新的GC,而这些 First, glucocorticoid (GC) drugs and their dynamic cortisol in the body in vivo conversion to cortisol to play a role. Respiratory disease GC is not as low as adrenal cortisol therapy to compensate, but the anti-inflammatory effect of GC or its immunosuppressive effect, in order to achieve the purpose of treatment. Therefore, there is a need for a more potent anti-inflammatory GC and for preventing its side effects, in particular reducing the electrolyte changes caused by cortisol. So far a lot of new GCs have been developed, and these