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目的:分析急性ST段抬高心肌梗死(STEMI)急诊PCI术中替罗非班冠脉直接注射的效果与安全性。方法:选取80例STEMI,随机分为冠脉组(40)与静脉组(40),冠脉组采取冠脉内推注持续泵入,静脉组采取静脉推注持续泵入。结果:注射后静脉组18例IRA TIMI血流3级(45.00%),冠脉组38例(95.00%),有明显差异(P<0.05)。静脉组9例IRA远端末梢栓塞(22.50%),冠脉组2例(5.00%),有明显差异(P<0.05)。结论:对于急性STEMI,在急诊PCI术中,冠脉应用替罗非班,安全有效。
Objective: To analyze the effect and safety of direct injection of tirofiban coronary artery in acute ST-segment elevation myocardial infarction (STEMI) emergency PCI. Methods: Eighty STEMI patients were randomly divided into coronary group (40) and intravenous group (40). The coronary artery was continuously pumped by intracoronary bolus. The intravenous bolus was injected continuously by intravenous injection. Results: There were significant differences (P <0.05) in IRA TIMI grade 3 (45.00%) in 18 cases and 38 cases (95.00%) in coronary group after injection. There were significant differences (P <0.05) in 9 cases of IRA distal end embolization (22.50%) and 2 coronary artery group (5.00%). Conclusion: For acute STEMI, Tirofiban is safe and effective for coronary artery in emergency PCI.