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目的:观察具有补肾壮骨、活血化瘀作用的牛淫合剂在治疗绝经后骨质疏松症及其疼痛方面的疗效。方法:将64例患者随机分为两组各32例,观察组予口服牛淫合剂;对照组予口服阿仑膦酸钠片治疗。对治疗后两组患者骨代谢指标、骨密度及疼痛改善情况进行观察,并进行统计学分析。结果:(1)两组患者治疗后骨代谢及骨密度均有明显改善,两组间差异无统计学意义(P>0.05)。(2)治疗后两组患者骨质疏松疼痛均有显著改善,差异无统计学意义(P>0.05)。结论:对于改善绝经后骨质疏松症患者的骨代谢异常及疼痛症状牛淫合剂有效,其疗效与阿仑膦酸钠片相仿。
OBJECTIVE: To observe the curative effect of Niu Yixi Mixture that has the functions of tonifying kidney, strengthening blood circulation and removing blood stasis in the treatment of postmenopausal osteoporosis and its pain. Methods: Sixty-four patients were randomly divided into two groups of 32 cases. The observation group was orally administered with Niuyin Mixture. The control group was treated with alendronate sodium tablets. After treatment, two groups of patients with bone metabolism indicators, bone mineral density and pain were observed, and statistical analysis. Results: (1) The bone metabolism and BMD of both groups were significantly improved after treatment, with no significant difference between the two groups (P> 0.05). (2) After treatment, the two groups of patients with osteoporosis pain were significantly improved, the difference was not statistically significant (P> 0.05). Conclusion: It is effective in improving the bone metabolism and pain symptoms in postmenopausal osteoporosis patients. It has the same efficacy as alendronate sodium tablets.