1引言扑尔敏又称马来酸氯苯那敏，为抗组织胺药，对各种过敏性疾病有良好的疗效。本文首次利用扑尔敏与氯冉酸在丙酮介质中发生的荷移反应，建立简便的分光光度法，对扑尔敏制剂中的有效成分进行含量测定。测定波长是536nm，表观摩尔吸光系数是1．38×103L·mol－1·cm－1，线 1 Introduction chlorpheniramine chlorpheniramine maleate, also known as antihistamines, have a good effect on a variety of allergic diseases. In this paper, for the first time, the charge-transfer reaction between chlorpheniramine and chlorpheniramine in acetone was used to establish a simple and convenient spectrophotometric method for the determination of the active ingredients in chlorpheniramine formulations. The measurement wavelength is 536nm, the apparent molar absorptivity is 1.38 × 103L · mol-1 · cm-1, the line