由于分子生物学技术的发展 ,大肠癌发生的分子机制研究取得了突破性进展。人们原来注重分析癌细胞本身的生物特性 ,现更注重对正常细胞演变为癌过程中基因水平的分析。认识到细胞癌变及恶性肿瘤发生、发展的根本原因可能在于细胞内部基因结构及表达的异常改变。大量研究表明 , Due to the development of molecular biology technology, the molecular mechanism of colorectal cancer has made breakthrough progress. People originally focused on analyzing the biological characteristics of cancer cells, and now pay more attention to the analysis of the gene level of normal cells into cancer. Realizing the fundamental reason of cell carcinogenesis and malignant tumor happening and developing may lie in abnormal changes of gene structure and expression in cells. A large number of studies have shown that,