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胃泌素/胆囊收缩素的受体拮抗剂丙谷胺是治疗溃疡的有效药,近几年来关于胆囊收缩素(CCK)受体的拮抗剂对离体胰腺腺泡分泌的影响研究较多,有文献报导丙谷胺可通过拮抗 CCK 受体而抑制低浓度 CCK 引起的离体胰腺腺泡的淀粉晦分泌。本试验旨在观察在没有外源性 CCK 刺激的情况下,丙谷胺对在体胰腺腺液分泌的效应。
Gastrin / cholecystokinin receptor antagonist Prothymine is an effective drug for the treatment of ulcer. In recent years, there are many studies on the effects of cholecystokinin (CCK) receptor antagonists on the secretion of isolated pancreatic acinar, It has been reported that proglumide inhibits the amyloid secretion of isolated pancreatic acinar by low CCK concentration by antagonizing the CCK receptor. This experiment aimed to observe the effect of proglumide on pancreatic glandular fluid secretion in the absence of exogenous CCK stimulation.