用胰岛素(I)、高血糖素(G)和生长抑素(Ss)3种抗血清作免疫组化染色,对在生后发育中的大鼠颔下腺进行光镜观察。结果:自生后第2周开始,3种抗血清的阳性反应产物定位于所有导管上皮细胞的核周质及顶部胞浆内。以后染色逐渐加强,至8周接近成体水平。用图像分析和放射免疫法测定其含量,以I最高,G次之,Ss最少。提示颔下腺导管系细胞可能是存在于消化道的另一组参与体内血糖平衡的内分泌细胞。 Immunohistochemical staining was performed with three kinds of antisera, insulin (I), glucagon (G) and somatostatin (Ss). Results: From the second week after birth, the positive reaction products of the three kinds of antiserum localized in the perinuclear and apical cytoplasm of all ductal epithelial cells. After staining gradually strengthened, to 8 weeks close to the adult level. Its content was determined by image analysis and radioimmunoassay. The highest I, the second G, and the least Ss. Tip hypogastric ductal cells may be present in the digestive tract of another group of endocrine cells involved in the body’s blood sugar balance.