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[目的]观察小青龙汤联合西药治疗慢性支气管炎急性发作疗效。[方法]使用随机平行对照方法,将100例住院患者按抛硬币法简单随机分为两组。对照组50例头孢噻肟钠2g+0.9%生理盐水250m L,2次/d,静滴;氨溴索,10mg/次,3次/d;沙丁胺醇,气雾吸入,1掀/次,3次/d。治疗组50例小青龙汤(麻黄4.5g,芍药12g,细辛3g,法半夏12g,五味子9g,鱼腥草18g,干姜9g,茯苓15g,橘红9g,甘草6g,紫苏子9g;胸闷加杏仁、厚朴各9g;出血加白及12g,仙鹤草15g),1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、症状缓解时间、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效41例,有效6例,无效3例,总有效率94.00%。对照组显效32例,有效4例,无效14例,总有效率72.00%。治疗组疗效优于对照组(P<0.01)。症状缓解时间治疗组短于对照组(P<0.01)。[结论]小青龙汤联合西药治疗慢性支气管炎急性发作疗效满意,无严重不良反应,值得推广。
[Objective] To observe Xiao Qinglong Decoction combined with western medicine in the treatment of acute exacerbation of chronic bronchitis. [Methods] Using randomized parallel control method, 100 inpatients were randomly divided into two groups according to the coin-tossing method. The control group 50 cases of cefotaxime sodium 2g + 0.9% saline 250m L, 2 times / d, intravenous infusion; ambroxol, 10mg / times, 3 times / d; salbutamol, aerosol inhalation, 1 lift / Times / d. The treatment group 50 cases of Xiao Qinglong Decoction (ephedra 4.5g, peony 12g, Asarum 3g, France Pinellia 12g, Schisandra 9g, Houttuynia 18g, ginger 9g, Poria 15g, orange 9g, licorice 6g, perilla 9g; Chest tightness plus almonds, Magnolia 9g; Bleeding plus 12g, Agrimony 15g), 1 / d, decoction 200m L, morning and evening oral; Western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observed clinical symptoms, symptoms, remission time, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 41 cases were markedly effective, 6 cases were effective, 3 cases were ineffective, and the total effective rate was 94.00%. The control group markedly effective in 32 cases, effective in 4 cases, ineffective in 14 cases, the total effective rate was 72.00%. The treatment group than the control group (P <0.01). The symptom relief time was shorter in the treatment group than in the control group (P <0.01). [Conclusion] Xiao Qing Long Decoction combined with western medicine in the treatment of acute exacerbation of chronic bronchitis has satisfactory curative effect and no serious adverse reactions, which deserves promotion.