围产期窒息可引起新生儿多脏器形态和功能的改变,其中以肾脏损害发生率最高。近年来,国内外学者已注意到重度窒息可导致急性肾功能衰竭。同时,人们也发现,测定患者的血、尿β_2—微球蛋白(β_2m)与血肌酐(Cr)、血尿素氮(BUN)一样,都可以反映患者的肾功能,并且血、尿β_2m比Cr、BUN能 Perinatal asphyxia can cause neonatal multiple organ changes in morphology and function, of which the highest incidence of renal damage. In recent years, domestic and foreign scholars have noticed that severe asphyxia can cause acute renal failure. At the same time, people also found that the measurement of blood and urine β_2-microglobulin (β_2m) and serum creatinine (Cr), blood urea nitrogen (BUN), can reflect the patient’s renal function, and blood, urine β_2m than Cr BUN can