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目的:观察中药益气健脾疏肝汤结合心理干预对乳腺癌术后化疗患者生活质量的影响。方法:将60例乳腺癌根治术后患者随机分为2组各30例。对照组只接受常规化疗;治疗组除接受常规化疗外,配合口服中药益气健脾疏肝汤及心理干预治疗。研究周期为12周。采用Zung焦虑量表(SAS)、抑郁量表(SDS)、生活质量核心问卷(EORTC QLQ-C30)和生活质量问卷-乳腺癌模式(EORTC QLQ-BR23)评定2组患者治疗前后心理状态及生活质量。结果:治疗组SAS、SDS评分均显著减少,QLQ-C30各项评分均显著增加,QLQ-BR23各项评分均显著改善,与治疗前及与对照组治疗后比较,差异均有显著性意义(P<0.05)。结论:益气健脾疏肝汤结合心理干预对乳腺癌术后化疗患者的抑郁和焦虑症状有显著改善作用,可以改善患者心理社会适应能力,提高生活质量。
Objective: To observe the effect of traditional Chinese medicine Yiqi Jianpi Shugan Decoction combined with psychological intervention on the quality of life of patients with postoperative chemotherapy of breast cancer. Methods: Sixty cases of breast cancer after radical operation were randomly divided into two groups of 30 cases. The control group received only conventional chemotherapy; the treatment group received routine chemotherapy, combined with oral medicine Yiqi Jianpi Shugan Tang and psychological intervention. The study period is 12 weeks. The psychological status and life before and after treatment were evaluated using the Zung Anxiety Scale (SAS), Depression Scale (SDS), Quality of Life Core Questionnaire (EORTC QLQ-C30) and Quality of Life Questionnaire-Breast Cancer Model (EORTC QLQ-BR23) quality. Results: The scores of SAS and SDS in the treatment group were significantly decreased, all the scores of QLQ-C30 were significantly increased, and all the scores of QLQ-BR23 were significantly improved, with significant difference between before treatment and after treatment P <0.05). Conclusion: Yiqi Jianpi Shugan Decoction combined with psychological intervention can significantly improve the depression and anxiety symptoms of postoperative chemotherapy in patients with breast cancer, which can improve patients’ psychosocial adaptability and improve their quality of life.