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作者用生产氯霉素的中间体—左旋氨基醇拆分d1-2-(6-甲氧基-2-萘基丙酸,首次成功地得到(+)-s-2-(6-甲氧基-2-萘基)丙酸即萘普生(Naproxen)。并研讨了温度、拆分剂用量等因素对拆分的影响。
The authors succeeded in obtaining (+) - s-2- (6-methoxy-2-naphthylpropionic acid for the first time using the intermediate of chloramphenicol, 2-naphthyl) propionic acid as naproxen, and the effects of temperature, the amount of resolving agent and other factors on the resolution were discussed.