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目的探讨米非司酮配伍米索前列醇药物流产临床疗效及相关影响因素。方法对我院妇产科门诊2002年1月10日～2009年11月10日接收的正常妊娠自愿要求药物流产的孕妇1268例,采用非司酮及米索前列醇药物流产,观察孕妇腹痛情况、阴道出血情况、胚胎组织排出时间、药物副作用等。结果药物流产后完全流产者占82.65%,不完全流产者占16.88%,药物流产的有效率占99.52%;服用米索前列醇后胚胎组织排出时间为90min～7d;阴道流血持续时间3～38d。恶心的发生率50%,腹痛的发生率81%。结论药物流产方法比较简便,对孕妇子宫内膜损伤较小,减轻了孕妇的痛苦,避免了人工流产进宫腔操作可能造成的并发症,容易被大多数孕妇接受,临床效果较好。
Objective To investigate the clinical efficacy and related factors of mifepristone and misoprostol medical abortion. Methods A total of 1268 pregnant women, who received voluntary abortion during normal pregnancy from January 10, 2002 to November 10, 2009, received obstetric and misoprostol medical abortion to observe abdominal pain in pregnant women , Vaginal bleeding, embryo tissue discharge time, drug side effects. Results After medical abortion, the total abortion accounted for 82.65%, incomplete abortion accounted for 16.88%, the effective rate of medical abortion accounted for 99.52%; taking misoprostol embryos after the discharge time of 90min ~ 7d; vaginal bleeding duration of 3 ~ 38d . The incidence of nausea was 50%, the incidence of abdominal pain was 81%. Conclusion The method of medical abortion is relatively simple and less damage to the endometrium of pregnant women, alleviating the pain of the pregnant women, avoiding the possible complications caused by the abortion into the uterine cavity and being easily accepted by most pregnant women, and the clinical effect is better.