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用α干扰素治疗慢性乙型肝炎３１例，并检测了治疗前后血清Ⅲ型前胶原水平。结果，治疗组疗程结束后血清Ⅲ型前胶原含量显著降低，而对照组无明显变化。表明干扰素可减轻慢性乙型肝炎患者肝内胶原增生的程度及活动性。
31 cases of chronic hepatitis B were treated with interferon - alpha, and the serum level of procollagen Ⅲ was detected before and after treatment. Results, the treatment group after treatment serum procollagen type Ⅲ was significantly lower, while the control group no significant change. Interferon can reduce the extent and activity of intrahepatic collagen hyperplasia in patients with chronic hepatitis B.