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目的了解本地区细菌性前列腺炎患者感染的病原菌种类及耐药情况,为临床治疗提供依据。方法对252例细菌性前列腺炎患者的前列腺液作细菌培养,用美国德灵公司MicroScanAutoSCAN4型细菌鉴定仪及药敏分析仪对分离的细菌进行鉴定及药敏试验。结果252例标本中,阳性154例,阳性率61.1%,以金黄色葡萄球菌为主,其次为大肠埃希菌和表皮葡萄球菌。药敏试验结果显示,常规使用的抗生素如青霉素G、氨苄西林、复方新诺明、环丙沙星等耐药率较高,在61.3%～83.9%,而对万古霉素、亚胺培南、阿米卡星、妥布霉素、利福平、左旋氧氟沙星等敏感性较高。结论细菌性前列腺炎患者的治疗,应以细菌培养及药敏试验结果为依据,指导临床合理选用抗菌药物。
Objective To understand the types and drug resistance of pathogenic bacteria in patients with bacterial prostatitis in this area and provide the basis for clinical treatment. Methods The prostatic fluid of 252 patients with bacterial prostatitis was cultured in vitro. The isolated bacteria were identified and susceptible tested by using the MicroScan AutoSCAN4 bacterial analyzer and drug susceptibility analyzer. Results Of the 252 specimens, 154 were positive, with a positive rate of 61.1%, mainly Staphylococcus aureus, followed by Escherichia coli and Staphylococcus epidermidis. Susceptibility test results showed that conventional antibiotics such as penicillin G, ampicillin, cotrimoxazole, ciprofloxacin and other high resistance rates, at 61.3% to 83.9%, while the vancomycin, imipenem , Amikacin, tobramycin, rifampin, levofloxacin and other high sensitivity. Conclusion The treatment of bacterial prostatitis patients should be based on bacterial culture and drug sensitivity test results to guide the rational use of antimicrobial agents in clinical practice.