【摘 要】
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In the mammalian central nervous system, neuronal loss induced by injuries or in neurodegenerative diseases is often irreversible (Quigley, 2016; Gan et al., 20
【机 构】
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Department of Biology,University of Virginia,Charlottesville,VA,USA;Department of Neurological Surge
论文部分内容阅读
In the mammalian central nervous system, neuronal loss induced by injuries or in neurodegenerative diseases is often irreversible (Quigley, 2016; Gan et al., 2018). Following the disease insult, the surviving neurons may continue to lose their functionality because their axons degenerate and fail to maintain proper synaptic connections, and the underlying molecular and cellular mechanisms remain to be investigated (Raff et al., 2002; Bei et al., 2016; Quigley, 2016).
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