肠相关淋巴组织在防御病毒、细菌、寄生虫等有害侵袭的过程中发挥着重要的屏障作用,其中肠道树突状细胞最为关键。作为最强有力的专职抗原递呈细胞,树突状细胞能够摄取、加工肠道微生物抗原和其他口服抗原,呈递给T细胞、B细胞、自然杀伤细胞等效应淋巴细胞并使之致敏,通过这些致敏淋巴细胞及其合成的特异性抗体、细胞因子清除有害的病原微生物,同时对肠道正常菌群以及口服抗原保持免疫耐受。 Gut-associated lymphoid tissue plays an important barrier role in the defense of viruses, bacteria, parasites and other harmful invasion, of which intestinal dendritic cells are the most critical. As the most potent professional antigen-presenting cell, dendritic cells are capable of uptake and processing of gut microbial antigens and other oral antigens, presenting to and sensitizing effector cells such as T cells, B cells and natural killer cells These sensitized lymphocytes and their synthetic specific antibodies, cytokines eliminate harmful pathogenic microorganisms, while maintaining normal intestinal flora and oral antigens immune tolerance.