发现1例HIV感染者在服用抗病毒药过程中出现一过性的无精子症,分析发现此现象是在用依非韦仑代替奈韦拉平之后,认为依非韦仑可能是导致HIV感染者一过性无精子症的主要原因。目前尚未见抗病毒药对男性生殖副作用的报道。此结果提示,HIV患者服用抗病毒药特别是依非韦仑过程中需监测精液质量。 One case of HIV-infected persons was found to have transient azoospermia during antiretroviral therapy. Analysis found that after efavirenz was given in place of nevirapine, efavirenz was considered as the likely cause of HIV infection The main reason of azoospermia. At present, there is no report of antiviral drugs on male reproductive side effects. This result suggests that semen quality needs to be monitored in HIV patients taking antiviral drugs, especially efavirenz.