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1.绪言 与Co-Cr系合金以及不锈钢等比较,作为人造股关节及人造齿根等硬组织替代器具构成材料多数使用生物体相容性好、比强度及耐蚀性良好的以Ti-6A14V-ELI合金为主的钛合金,但是,Ti-6A1-4V-ELI合金含有V等合金元素,当其在体内组织中溶出时,有可能引起细胞毒性及神经毒性。为此,须开发以对人体危害性可忽略不计的合金元素为主体的生物体用钛合金。例如,日
1. Introduction Compared with Co-Cr series alloys and stainless steels, Ti-6A14V (Ti-6Al4V) alloy is widely used as a substitute material for hard tissue substitutes such as artificial joints and artificial tooth roots, and has good biocompatibility and specific strength and corrosion resistance. -ELI alloy. However, Ti-6A1-4V-ELI alloy contains alloying elements such as V and may cause cytotoxicity and neurotoxicity when it is eluted in the body tissues. To this end, it is necessary to develop titanium alloys for biological use that are mainly composed of alloying elements that are negligible to the human body. For example, day