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目的研究肿瘤化疗患者并发败血症病原菌分布及耐药特点,为临床合理用药提供依据。方法通过回顾性调查,了解某医院住院肿瘤化疗患者并发败血症病原菌分布与耐药特征。结果该医院在2007-2012年期间从败血症病人血标本中共分离出病原菌287株,其中革兰阳性菌占50.9%,革兰阴性菌占38.0%,真菌占11.1%。肠球菌和鲍曼不动杆菌成为最严重的耐药菌。结论败血症病原菌以革兰阳性菌为主,且呈上升趋势,多种病原菌耐药情况严重。
Objective To study the distribution of drug-resistant pathogens and sepsis in patients with tumor chemotherapy and provide basis for clinical rational drug use. Methods The retrospective investigation was conducted to find out the distribution and drug resistance characteristics of sepsis pathogens in hospitalized patients with chemotherapy in the hospital. Results A total of 287 pathogens were isolated from blood samples of sepsis patients from 2007 to 2012 in the hospital. Among them, Gram-positive bacteria accounted for 50.9%, Gram-negative bacteria accounted for 38.0% and fungi accounted for 11.1%. Enterococcus and Acinetobacter baumanni become the most serious resistant bacteria. Conclusion The main pathogens of sepsis are Gram-positive bacteria, and they are on the rise. The resistance of many pathogens is serious.