论文部分内容阅读
目的 探讨北京地区成人急性呼吸道感染(ARI)患者9种常见病毒的感染情况,分析病原体流行病学特征.方法 采用ELISA法检测1887例ARI患者巨细胞病毒(CMV)、EB病毒(EBV)、柯萨奇病毒(CVB),单纯疱疹病毒Ⅰ型和Ⅱ型(HSV-Ⅰ和HSV-Ⅱ),腺病毒3、7和11型(ADV3、ADV7和ADV11)及风疹病毒(RV)等9种病原体IgM抗体.结果 1887例标本中共检出阳性706例,总感染率为37.41％(706/1887),其中CMV感染率最高为10.92％,其次为HSV-Ⅰ(9.59％),其它病原体检出率由高到低依次为ADV7、ADV11、EBV、ADV3、HSV-Ⅱ、CVB和RV.混合感染者有260例,占36.83％ (260/706).10月份感染率最高,4月份感染率最低,且各病原体的流行季节也不同.病例以中青年感染者居多,不同性别间感染率差异无显著性.结论 2014年北京地区存在多种病原体流行,以CMV、HSV-Ⅰ和ADV7为主要病原体,各病原体流行有季节性特点.“,”Objective To characterize the infection status of viral pathogens in adults with acute respiratory infections(ARI) in Beijing area and explore the epidemiological characteristics of 9 viruses.Methods A total of 1887 cases of ARI were sampled and detected for 9 respiratory viruses (CMV 、EBV 、CVB、HSV-Ⅰ、HSV-Ⅱ、ADV3、ADV7、ADV11 and RV) IgM antibody using ELISA kit.Results A total of 706 cases of ARI were tested positive accounting for 37.41％ (706/1887).CMV had the highest positive rate of 10.92％ (206/1887),followed by HSV-Ⅰ (9.59％,181/1887),the next were ADV7 、ADV11 、EBV 、ADV3、HSV-Ⅱ、CVB and RV in turn.While 260 out of 706 cases positive were mixed-infected with the proportion of 36.83％.The highest detection rate of viruses was observed in October,whereas the lowest in April.Distinct pathogens had different prevalent features.Middle-aged people constituted the majority of infection cases.There was no statistical gender difference detected in term of infection.Conclusions There were various pathogens simultaneously prevalent during 2014 in Beijing area.CMV、HSV-Ⅰ and ADV7 accounted for majority of viral etiology spectrum of ARI in adults.Prevalence of different pathogens presented seasonal characteristics.