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报道25例以神经症状为首发表现的恶性淋巴瘤:脊髓或马尾13,脑7,颅神经5。淋巴肉瘤10(均椎管硬脊膜外转移),网状细胞肉瘤8(脑肿瘤6,颅底转移1,软脑膜转移 1),Hodgkin淋巴瘤1(颅底转移),未定型恶性淋巴瘤6(椎管内转移3,脑肿瘤1,软脑膜转移1,眶内转移1)。除1例外,均于起病初或不久即有相应神经的疼痛,随病程而愈益剧烈。17例有身体其他系统或部位受累的表现。10例有不明原因发热。都通过淋巴结、肿块、鼻咽部活检或手术探查而明确病理诊断。2例淋巴瘤硬脊膜外转移因激素治疗有短期好转而稍迟才确诊。
Reported 25 cases of neurological symptoms as the first manifestation of malignant lymphoma: spinal cord or cauda equina 13, brain 7, cranial nerve 5. Lymphosarcoma 10 (all spinal canal extradural metastases), reticulocytic sarcoma 8 (brain tumor 6, skull base metastasis 1, pia mater metastasis 1), Hodgkin’s lymphoma 1 (skull base metastasis), undetermined malignant lymphoma 6 (spinal canal metastasis 3, brain tumor 1, pia mater metastasis 1, orbital metastasis 1). In addition to one exception, both in the beginning or soon onset of the corresponding nerve pain, with the course of the more intense. 17 cases of other body parts or parts involved in the performance. 10 cases have unexplained fever. Through the lymph nodes, lumps, nasopharyngeal biopsy or surgical exploration and clear pathological diagnosis. Two cases of extralympional lymphoma metastasis due to hormone therapy short-term improvement and later confirmed.