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有机磷化合物如农药等对人及动物毒性较大,国内外对其进行了多方面的研究,发现双吡啶季铵盐类有抗毒作用。1976年Schoene报道了P_(65)与阿托品伍用具有防护小鼠有机磷化合物中毒作用。
Organophosphorus compounds, such as pesticides, are more toxic to humans and animals. They have been studied in various fields both at home and abroad and found that bipyridine quaternary ammonium salts have antitoxic effects. Schoene in 1976 reported the P_ (65) and atropine Wudu with protective organophosphate poisoning in mice.