论文部分内容阅读
目的观察舒血宁联合脑蛋白水解注射液治疗脑梗死患者的临床效果。方法选取医院收治的脑梗死患者120例(经CT或MR确诊),随机分为观察组和对照组,每组60例。对照组给予舒血宁注射液20 ml加入5%葡萄糖液或生理盐水250 ml静脉滴注,每天1次;观察组在此基础上,间隔2 h给予脑蛋白水解注射液40 ml加入生理盐水250 ml静脉滴注,每天1次。观察2组患者临床效果及治疗前后NIHSS评分、活化的部分凝血活酶时间(APTT)、纤维蛋白原(Fib)变化及不良反应。结果观察组总有效率为83.3%,高于对照组的65.0%(P<0.05);2组患者治疗后NIHSS评分、APTT、Fib均改善,且观察组优于对照组(P均<0.01)。结论舒血宁联合脑蛋白水解注射液治疗脑梗死较单纯应用舒血宁临床疗效好,值得临床推广应用。
Objective To observe the clinical effect of Shuxuening combined with brain proteolytic injection in patients with cerebral infarction. Methods Totally 120 patients with cerebral infarction admitted to the hospital (diagnosed by CT or MR) were randomly divided into observation group and control group, with 60 cases in each group. The control group was given Shuxuening injection 20 ml added 5% glucose solution or saline 250 ml intravenous infusion, once a day; the observation group on this basis, at intervals of 2 h given brain proteolytic injection 40 ml added saline 250 ml intravenously, once daily. The clinical effects, NIHSS score, activated partial thromboplastin time (APTT), fibrinogen (Fib) changes and adverse reactions in both groups were observed before and after treatment. Results The total effective rate in observation group was 83.3%, which was higher than that in control group (65.0%, P <0.05). NIHSS score, APTT and Fib in both groups were improved after treatment, and the observation group was better than the control group (all P <0.01) . Conclusion Shuxuening combined with brain proteolytic injection of cerebral infarction than the simple application of Shuxuening clinical efficacy, worthy of clinical application.