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目的:评价甲钴胺联合脉络宁治疗糖尿病周围神经病变的临床疗效。方法:将80例糖尿病周围神经病变患者随机分为2组,治疗组40例,给予甲钴胺0.5mg/次,口服3次/天,同时予脉络宁20ml+生理盐水250ml静脉滴注。对照组40例,单用甲钴胺0.5mg/次口服3次/天,2组疗程均为4周,观察临床疗效。结果:治疗组总有效率为87.5%,对照组总有效率为75%,2组间比较差异有统计学意义(P<0.05)结论:甲钴胺联合脉络宁治疗糖尿病周围神经病变较单用甲钴胺治疗临床效果好。
Objective: To evaluate the clinical efficacy of mecobalamin combined with Mailuoning in the treatment of diabetic peripheral neuropathy. Methods: Eighty patients with diabetic peripheral neuropathy were randomly divided into two groups. The treatment group was given 40 mg mecobalamin 0.5 mg once daily orally 3 times a day, and given Mailuoning 20ml plus normal saline 250ml intravenously. Control group of 40 patients, mecobalamin alone 0.5mg / time orally 3 times / day, 2 groups were 4 weeks course of treatment, observation of clinical efficacy. Results: The total effective rate was 87.5% in the treatment group and 75% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion: Mecobalamin combined with Mailuoning treatment of diabetic peripheral neuropathy than single use Mecobalamin treatment of clinical effect.