论文部分内容阅读
目的:探索可吸收医用膜应用于重度宫腔粘连(IUA)的临床疗效及对妊娠结局的影响。方法:选取2014年7月至2016年8月就诊于常州市妇幼保健院的60例重度IUA患者,随机分为观察组(n=30)和对照组(n=30)。两组患者均行宫腔粘连分离术(TCRA),并放置充水球囊并服用雌孕激素人工周期药物,观察组术后在此基础上加用可吸收医用膜。比较两组患者的临床疗效及妊娠情况。结果:观察组患者的宫腔引流量明显低于对照组,内膜厚度、宫腔容积及宫腔内血流指数均明显高于对照组,差异均有统计学意义(P<0.05)。两组患者的月经量较术前均明显改善,但观察组患者的改善程度优于对照组(P<0.05)。观察组患者的临床有效率高于对照组,首次妊娠时间短于对照组,差异均有统计学意义(P<0.05)。两组患者的妊娠率和自然流产率比较,差异均无统计学意义(P>0.05)。结论:重度IUA患者TCRA后放入可吸收医用膜可明显改善月经量及宫腔情况,缩短妊娠时间,预防宫腔再粘连。
Objective: To explore the clinical efficacy of absorbable medical membrane for severe intrauterine adhesions (IUA) and its effect on pregnancy outcome. Methods: Sixty patients with severe IUA who were treated in Changzhou MCH from July 2014 to August 2016 were randomly divided into observation group (n = 30) and control group (n = 30). The two groups of patients underwent intrauterine adhesions (TCRA), and placed water-filled balloon and taking estrogen and progesterone artificial period drugs, the observation group on the basis of the use of absorbable medical membrane. The clinical efficacy and pregnancy status of the two groups were compared. Results: The uterine drainage volume in the observation group was significantly lower than that in the control group. The intima thickness, intrauterine volume and intrauterine blood flow index were significantly higher in the observation group than those in the control group (P <0.05). Menstrual volume in both groups was significantly improved compared with preoperative, but the improvement in observation group was better than that in control group (P <0.05). The clinical effective rate in the observation group was higher than that in the control group, the first pregnancy was shorter than the control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in pregnancy rate and spontaneous abortion rate (P> 0.05). Conclusion: The TCRA in patients with severe IUA can be absorbed into the medical membrane can significantly improve menstrual flow and uterine cavity conditions, shorten the pregnancy time, prevention of intrauterine reunion.