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目的对比头孢他啶和头孢哌酮治疗儿童重型细菌性痢疾的疗效。方法 40例急性重型细菌性痢疾患儿 ,随机分为头孢他啶组和头孢哌酮组 ,每组各 2 0例。结果 40例患儿均于治疗后 2 4小时内病情明显好转 ,多数在 1～ 2日内退热 ,便次及其性状、便常规及血象恢复时间均在 3～ 5日内恢复正常 ,治愈率 10 0 % ,两组比较无显著性差异 (P>0 .0 5 )。粪便细菌培养均在 3日内阴转 ,阴转率 10 0 % ,两组比较无显著性差异 (P>0 .0 5 )。结论头孢他啶与头孢哌酮钠治疗重型儿童细菌性痢疾疗效均好 ,安全
Objective To compare the efficacy of ceftazidime and cefoperazone in the treatment of children with severe bacillary dysentery. Methods Forty patients with acute severe bacillary dysentery were randomly divided into ceftazidime group and cefoperazone group, with 20 cases in each group. Results 40 cases of children were significantly improved within 24 hours after treatment, most of the 1 to 2 days in the fever, the times and their traits, routine and blood recovery time were returned to normal within 3 to 5 days, the cure rate 10 0%, no significant difference between the two groups (P> 0.05). Fecal bacterial culture were within 3 days of negative conversion, negative conversion rate of 10%, no significant difference between the two groups (P> 0.05). Conclusion Ceftazidime and cefoperazone sodium are effective and safe in treating children with bacillary dysentery