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作者报告3例因原发性脑瘤经高剂量照射分别在5、12及15年后发生颅内脑膜瘤的病例,并结合文献加以讨论.例1:男,8岁时因小脑成神经管细胞瘤作包括全脑的整个神经轴照射,剂量50Gy,瘤床补充30Gy(即后颅窝为80Gy),脊髓40Gy.15年后于小脑桥脑角与矢状窦后部发生典型的变形脑膜瘤.例2:男,17岁时因L_1~L_2区粘液乳头状室管膜瘤作全切.4年后第四脑室与右小脑半球发生室管膜瘤作部分切除,术后全神经轴照射50Gy.5年后在右顶部与矢状窦旁发生脑膜瘤.
The authors report three cases of intracranial meningioma occurring at 5, 12 and 15 years after high-dose irradiation of primary brain tumor, respectively, and are discussed in the literature.Example 1: Male, 8 years old due to cerebellar neural tube The entire neuronal axis, including whole brain, was irradiated with a dose of 50Gy and the tumor bed was supplemented with 30Gy (80Gy posterior fossa) Tumor.Example 2: Male, due to L_1 ~ L_2 region mucinous papillary ependymoma at 17 years of age.After 4 years, the fourth ventricle and the right hemisphere of the ependymoma for partial resection, all the axons Radiation 50Gy.5 years after birth in the Department of labor and the occurrence of quadrilateral tumor were born tumor.