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目的:分析与探讨HPV感染与宫颈病变之间的关系,并深入剖析其相关危险因素。方法:以我院在2011年3月-2014年5月收治的150例宫颈细胞标本进行HPV基因型的分型检测与液基细胞学检查。细胞学诊断≥ASCUS以及HPV检测为阳性的受检者行阴道镜活检。结果:HPV检测阳性率为26.3%(39/150),液基细胞学≥ASCUS为25.9%(38/150)。细胞学诊断阳性率≥LSIL18.7%(28/150)与组织学诊断阳性≥CINI22.3%(33/150),两者相比较而言,差异无显著性特征。本组HPV感染共检出16种亚型,高危型81.3%,低危型18.7%。结论:HPV分型检测能够有效明确基因类型,将其联合液基细胞学与组织学那个有效对宫颈病变细胞进行筛查,从而为有效预防宫颈癌提供理论与科学上的依据。
Objective: To analyze and explore the relationship between HPV infection and cervical lesions, and to further analyze the related risk factors. Methods: The genotypes of HPV genotypes and liquid-based cytology were detected in 150 cases of cervical cell samples from March 2011 to May 2014 in our hospital. Cytological diagnosis ≥ASCUS and HPV test positive for the subjects colposcopy biopsy. Results: The positive rate of HPV testing was 26.3% (39/150), and the liquid-based cytology ≥ASCUS was 25.9% (38/150). Cytological positive rate ≥ LSIL18.7% (28/150) and histological positive ≥CINI22.3% (33/150), the two compared, the difference was not significant. This group of HPV infections were detected in 16 subtypes, high-risk type 81.3%, low-risk type 18.7%. Conclusion: HPV genotyping can effectively identify genotypes, and combined with liquid-based cytology and histology that effectively screening for cervical lesions so as to provide theoretical and scientific basis for the effective prevention of cervical cancer.