Objective To evaluate the application value and efficacy on stent place for Budd-Chiari syndrome (BCS).Methods From January 1990 to May 2017,2228 patients with BCS were admitted to our institution.The mean age was 43.3 years.Stents were placed in inferior vena cava (IVC),hepatic vein (HV),or both after balloon dilation.During follow-up period,the patency of stent was evaluated by ultrasound regularly and the clinic sign was surveyed by letter,telephone or clinic visit.The restenosis of stent were treated with balloon dilatation and thrombolysis to restore the its function.Results IVC type was diagnosed in 1492 cases,HV type in 510 cases,and mixed type in 226 cases.Eighteen patients aborted treatment because of economic reasons,advanced liver cancer,severe scoliosis,or both bilateral iliac veins and total IVC occlusion.Among the other 2210 cases who underwent endovascular therapy,stents were implanted into IVC in 339 cases,HV in 97 cases,mixed type in 64 cases.The rate of restenosis in IVC stent was 11.50％ (39/339).After repeat angioplasty,the long-term patency rate reached to 98.12％.The incidence of HV occlusion caused by IVC stent was 12.09％ (n =41).Restenosis occurred in 47 cases (48.45％) after HV stent placement.However,the 5-year patency rate was 91.75％ (89/97) after repeat dilatation and stent re-implantation.The incidence of IVC obstruction caused by HV was 3.33％ (3 cases).Conclusion IVC stent placement appears to be an effective treatment for the cases of IVC segmental occlusion,and at the same time,the stent has the dual role of compression and fixation of thrombus and support of lumen.The HV and accessory hepatic vein obstruction could happen when the IVC stent crossed these veins ostium.The incidence of the stent restenosis in the HV was higher than that in the IVC.