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目的:观察新辅助化疗在结直肠癌伴梗阻病人中的作用。方法:选取结直肠癌伴梗阻的病人16例,按改良FOLFOX6方案给予新辅助化疗2个疗程,间隔2周,并同时按照肠道功能情况给予肠外或肠内营养支持,化疗结束后2周内予以手术治疗。结果:所有病人在接受新辅助化疗后梗阻均得到了不同程度的缓解。所有病人均接受了一期切除吻合手术,术后恢复良好,无并发症发生。结论:在结直肠癌伴梗阻病人的治疗中,新辅助化疗可以缓解梗阻,为一期切除吻合手术创造条件。
Objective: To observe the role of neoadjuvant chemotherapy in patients with colorectal cancer and obstruction. Methods: Twenty-six patients with colorectal cancer with obstruction were selected. Two courses of neoadjuvant chemotherapy were given according to the modified FOLFOX6 regimen. Two weeks apart, parenteral or enteral nutrition was given according to the function of intestinal tract. After two weeks Within the surgery. Results: All patients had different degrees of remission after neoadjuvant chemotherapy. All patients underwent a one-stage resection and anastomosis surgery, postoperative recovery was good, no complications. Conclusion: In the treatment of patients with colorectal cancer and obstruction, neoadjuvant chemotherapy can relieve the obstruction and create the conditions for the one-stage resection and anastomosis.