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为确定甲状腺肿的生理性增大和病理性增大的界限,我们选择7-14岁儿童536例,重新探讨了甲状腺生理性增大的标准。先以本人小指末节大小为界,共调查536例,将其分成小于此界限的A组,大于小指末节而小于拇指末节的B组,和大于此界限的弥漫型I°增大的C组。分别进行T_4、TSH、吸~131Ⅰ率及尿碘的测定,以及其临床转归的观察。并将A、B组与C组互相作了比较,结果表明,A、B两组的T_4、TSH值与国内部分地区儿童正常值比较,差异显著(P<0.01),且B组与C组相对比,差异亦显著(P<0.01)。同时,对B组给予治疗与不治疗进行对比,临床转归截然不同,前者腺体复原率增高,T_4、TSH达正常水平,而后者则病情加重。由此认为地甲病生理性增大应以小指末节大小为标准,小于此者为生理性增大,而大于此者不是生理性增大范围,而属于早期病理性增大,故提出在此范围内应提倡采取治疗措施。
To determine the physiological increase of goiter and the pathological increase of the limit, we choose 536 children aged 7-14 so as to re-explore the physiological increase in thyroid criteria. A total of 536 cases were investigated with the size of the distal part of the little finger as a group, divided into group A smaller than this limit, group B larger than distal part of the little finger and distal part of the thumb, and diffuse I ° C group larger than this limit. Respectively, T_4, TSH, suction ~ 131 Ⅰ rate and urinary iodine determination, and the clinical outcome of the observation. The results showed that the values of T_4 and TSH in groups A and B were significantly different from the normal values in some parts of China (P <0.01), and the differences between groups B and C The difference was also significant (P <0.01). At the same time, the treatment of group B compared with no treatment, the clinical outcome is very different, the former increased the rate of glandular recovery, T_4, TSH up to normal levels, while the latter aggravate. Therefore, the increase of physiology of dementia should be based on the size of the distal part of the little finger as the standard, smaller than this is a physiological increase, while greater than this is not a physiological increase in the range, which belongs to the early pathological increase, it is proposed here Within the scope of treatment should be advocated.