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目的观察米索前列醇联合缩宫素治疗子宫收缩乏力性产后出血的疗效。方法选取徐州市贾汪区第三人民医院2013年6月—2015年11月收治的子宫收缩乏力性产后出血患者80例,根据不同的治疗方法分为观察组和对照组,各40例。观察组采用米索前列醇+缩宫素疗法,对照组单纯使用缩宫素治疗,比较两组患者不同时段的出血量及不良反应发生情况。结果观察组用药2、6、12h时的出血量少于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为7.5%(3/40),低于对照组的25.0%(10/40),差异有统计学意义(P<0.05)。结论米索前列醇联合缩宫素治疗子宫收缩乏力性产后出血疗效显著,可有效控制出血量,安全性好。
Objective To observe the curative effect of misoprostol combined with oxytocin on postpartum hemorrhage of uterine atony. Methods Eighty patients with postpartum hemorrhage of uterine atony in the Third People’s Hospital of Jiawang District of Xuzhou City from June 2013 to November 2015 were selected and divided into observation group and control group according to different treatment methods, 40 cases in each group. The observation group was treated with misoprostol + oxytocin, while the control group was treated with oxytocin alone. The amount of bleeding and the incidence of adverse reactions were compared between the two groups at different time points. Results The bleeding volume in observation group was less than that in control group at 2, 6 and 12 hours (P <0.05). The adverse reaction rate in observation group was 7.5% (3/40), which was lower than that in control group % (10/40), the difference was statistically significant (P <0.05). Conclusion Misoprostol combined with oxytocin treatment of uterine atony postpartum hemorrhage significant effect, can effectively control the amount of bleeding, good safety.