姜黄素是一种从印度咖喱粉分离出的天然混合物,几个世纪之前已经开始作为多种疾病的传统治疗方法。近年来发现姜黄素在肿瘤的预防和治疗方面的潜在利用价值。Amin等发现姜黄素诱导上呼吸道和消化道肿瘤细胞凋亡受多种信号通路的调节,如p73的诱导、p-AKT和Bcl-2的抑制。姜黄素处理过的头颈部和肺癌细胞系诱导产生p53和相关蛋白p73。p73显 Curcumin, a natural mixture isolated from Indian curry powder, has been used centuries ago as a traditional treatment for many diseases. In recent years, curcumin has been found to have potential value in the prevention and treatment of tumors. Amin and other found that curcumin induced upper respiratory and gastrointestinal tumor cell apoptosis by a variety of signaling pathways, such as the induction of p73, p-AKT and Bcl-2 inhibition. Curcumin-treated head and neck and lung cancer cell lines induce the production of p53 and related protein p73. p73 significant