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细菌性阴道病(BV)是育龄妇女最常见的阴道感染性疾病,与阴道内微生态平衡失调相关,患者阴道内乳杆菌减少,尤其是产过氧化氢乳杆菌减少,而阴道加德纳菌、阴道阿托波菌、动弯杆菌、人型支原体以及其他厌氧菌的异常增多[1-2]。BV与妇科手术感染、胎膜早破、自然流产、早产、绒毛膜炎、产褥感染、宫颈上皮细胞内瘤样变等发生相关,可增加人类免疫缺陷病毒(HIV)感染概率。另外,BV患者中交叉感染支原体、真菌、滴虫非常普遍[3]。因此,BV的检测对女性生殖系统疾病的诊断和防治具有重要的意义。1 BV诊断标准Amsel法为目前临床诊断BV的金标准[4],以下4个临床
Bacterial vaginosis (BV) is the most common vaginal infectious disease in women of childbearing age, associated with vaginal microflora imbalance, with decreased lactobacilli in the vagina, especially in Lactobacillus perfor- , Vitex vaginalis, Klinebacterium marnes, Mycoplasma hominis and other anaerobic bacteria abnormal increase [1-2]. BV and gynecological surgery, premature rupture of membranes, spontaneous abortion, premature delivery, chorionitis, puerperal infection, cervical intraepithelial neoplasia and other related occurrence, can increase the probability of human immunodeficiency virus (HIV) infection. In addition, cross-infection in patients with BV mycoplasma, fungi, trichomoniasis is very common [3]. Therefore, the detection of BV is of great significance to the diagnosis and prevention of female reproductive system diseases. 1 BV diagnostic criteria Amsel method is currently the gold standard for clinical diagnosis of BV [4], the following four clinical