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目的评价曲美他嗪治疗老年女性非ST段抬高性心梗心功能2至3级患者的临床疗效方法选择符合诊断标准的患者82例,随机分为治疗组及对照组,两组均行常规治疗并口服氯吡格雷六个月,同时治疗组口服曲美他嗪,观察两组心功能和心绞痛的改善情况及心血管事件。结果治疗组与对照组比较,总有效率为90.4%和70.0%,心功能有明显改善,复发心绞痛明显减少(P<0.05),治疗组的心血管事件较对照组少但无统计学意义。结论在常规治疗的基础上使用氯吡格雷双重抗血小板治疗及曲美他嗪对老年女性非ST抬高性心梗有一定的疗效
Objective To evaluate the clinical efficacy of trimetazidine in the treatment of elderly patients with grade 2 to 3 patients with non-ST-segment elevation myocardial infarction. Methods Eighty-two patients with diagnostic criteria were randomly divided into treatment group and control group. Both groups received routine treatment And oral clopidogrel six months, while the treatment group oral trimetazidine, two groups of patients to observe the improvement of cardiac function and angina and cardiovascular events. Results Compared with the control group, the total effective rate was 90.4% and 70.0% in the treatment group. The cardiac function was significantly improved and the recurrent angina was significantly decreased (P <0.05). The cardiovascular events in the treatment group were less than those in the control group but not statistically significant. Conclusions The use of clopidogrel dual antiplatelet therapy and trimetazidine on elderly patients with non-ST-elevation myocardial infarction has a certain effect on the basis of conventional treatment