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目的:分析东莞市黄江医院药品不良反应(ADR)发生的特点和规律,促进临床合理用药。方法:采用回顾性调查方法对东莞市黄江医院2014年1月1日至2016年12月31日间发生的106份ADR报告进行分析。结果:ADR患者使用药品种类主要为抗菌药(43.40%),其次分别为循环系统药(21.70%)、消化系统药(19.81%);ADR患者主要给药途径为静脉滴注(73.58%),而后依次为口服(15.09%)、皮内注射(5.66%)、静脉注射(3.77%)、肌肉注射(1.89%);ADR患者症状表现主要为药物过敏、肝损害、中毒、癫痫等;ADR患者经治疗后,治愈率为65.09%,好转率为27.36%,总有效率为92.45%。结论:临床医药工作者应加强对药品不良反应的监测,尽可能减少药品不良反应的发生。
Objective: To analyze the characteristics and rules of adverse drug reaction (ADR) in Huangjiang Hospital of Dongguan City and promote the rational use of drugs in clinic. Methods: A retrospective survey method was used to analyze 106 ADR reports that occurred in Dongguan Huangjiang Hospital from January 1, 2014 to December 31, 2016. Results: The main types of drugs used in patients with ADR were antimicrobial drugs (43.40%), followed by circulatory system drugs (21.70%) and digestive system drugs (19.81%) respectively. The main routes of administration for ADR patients were intravenous drip (73.58% Followed by oral (15.09%), intradermal injection (5.66%), intravenous injection (3.77%), intramuscular injection (1.89%); ADR patients with symptoms mainly drug allergies, liver damage, poisoning, epilepsy; ADR patients After treatment, the cure rate was 65.09%, the improvement rate was 27.36%, the total effective rate was 92.45%. Conclusion: Clinical medical workers should strengthen the monitoring of adverse drug reactions, as much as possible to reduce the incidence of adverse drug reactions.