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测定了50例脑部疾病患者脑脊液胰岛素、皮质醇、睾酮、雌二醇的含量,并设25例非神经科手术患者对照,结果胰岛素含量显著低于对照组(4.07±2.22比9.44±7.53,P<0.01),提示脑损伤时补充胰岛素具有积极的治疗意义。男性脑脊液中睾酮显著低于对照组(P<0.01)。皮质醇、雌二醇及女性睾酮与对照组无统计学差异,提示脑部疾病对其在脑脊液中的含量影响不大。
The contents of insulin, cortisol, testosterone and estradiol in cerebrospinal fluid (CSF) were measured in 50 patients with brain disease. The control group was given 25 patients with non-neurological surgery. The results showed that the insulin content was significantly lower than that of the control group (4.07 ± 2.22 vs 9.44 ± 7.53, P <0.01), suggesting that insulin supplementation in brain injury has a positive therapeutic value. Testosterone in male CSF was significantly lower than that in control group (P <0.01). Cortisol, estradiol and female testosterone had no significant difference with the control group, suggesting that brain disease has little effect on the content in cerebrospinal fluid.