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目的分析龙门县围产期出生缺陷的临床现状,为临床干预制定策略提供依据。方法采用回顾性分析龙门县2012年~2014年孕满28周至生后一周的所有的出生缺陷情况,分析该县各出生缺陷的发病现状并探寻相应的干预措施。结果果分析结果显示,龙门县2012~2014年10107例围产儿中出生缺陷的总发生率为12.27‰,按照发生率的高低居前5位的出生缺陷为指(趾)畸形4.16‰、唇腭裂2.57‰、复合畸形2.08‰、足内翻1.88‰、无脑儿及脑积水1.58‰。结论目前龙门县出生缺陷虽然低于国家的总发生率(l3.7‰),但仍然偏高,如果采取相应的干预策略,还可以再降低围产儿出生缺陷的发生率,提高出生人口素质。
Objective To analyze the clinical status of perinatal birth defects in Longmen County and provide the basis for the formulation of clinical intervention strategies. Methods A retrospective analysis of all birth defects in Longmen County during the period from 28 weeks of pregnancy to one week after birth in 2012-2014 was conducted to analyze the incidence of birth defects in each county and explore corresponding intervention measures. Results Analysis of the results showed that the total incidence of birth defects in 10107 cases of perinatal children from 2012 to 2014 in Longmen County was 12.27 ‰. According to the incidence rate, the top 5 birth defects were 4.16 ‰ of deformities of the digits, cleft lip and palate 2.57 ‰, complex deformity 2.08 ‰, foot varus 1.88 ‰, no brain children and hydrocephalus 1.58 ‰. Conclusions Although the birth defect in Longmen County is lower than the national total incidence (l3.7 ‰), it is still high. If corresponding intervention strategies are adopted, the incidence of birth defects in perinatal children can be further reduced and the quality of the birth population raised.