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系统性红斑狼疮(SLE)是累及多系统的自身免疫性疾病,狼疮性肾炎(LN)是其最多见、最重要的表现之一。抗疟药是治疗SLE及LN的重要药物之一,临床应用日渐广泛。本文主要介绍抗疟药的作用机制、治疗SLE和LN的疗效及不良反应等。
Systemic lupus erythematosus (SLE) is a multi-systemic autoimmune disease involving lupus nephritis (LN) as one of its most common and important manifestations. Antimalarial drugs are one of the important drugs for the treatment of SLE and LN, and their clinical application is increasingly widespread. This article describes the mechanism of anti-malarial drugs, the treatment of SLE and LN efficacy and adverse reactions.