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目的探讨胶囊内镜(capsule endoscope,CE)在小肠克罗恩病(Crohn’disease,CD)诊断中价值。方法回顾性分析2009年9月至2014年5月期间已确立结肠CD诊断(established CD,e CD)的20例患者和疑诊小肠CD(sus-pected CD,s CD)的21例患者的胶囊检查资料。结果 eCD组13例发现小肠CD病变,sCD组10例诊断小肠CD,所有诊断小肠CD的23例患者中12例表现为糜烂/浅溃疡、11例深溃疡,7例溃疡合并狭窄,5例溃疡合并出血,4例溃疡伴结节样改变;病变位于在空肠3例(13.0%),空及回肠16例(69.6%),只在回肠4例(17.4%)。回盲瓣通过率70.7%(29/41),3例胶囊无症状滞留,1例肠镜下取出,另外2例分别在26 d和53 d排出。结论在eCD和sCD患者中,胶囊内镜可作为小肠CD安全有效的检查手段,对判定小肠CD黏膜损害的程度、范围有较高的诊断价值。
Objective To investigate the value of capsule endoscopy (CE) in the diagnosis of small bowel Crohn’s disease (CD). Methods A retrospective analysis of 20 patients with established CD, e CD and 21 patients with suspected small intestine CD (suspicious CD) from September 2009 to May 2014 was conducted. Check the information. Results 13 cases of small bowel CD lesions were found in eCD group, 10 cases of diagnosis of small bowel CD in sCD group, 12 cases of erosion / superficial ulcer, 11 cases of deep ulcer, 7 cases of ulcer with stenosis and 5 cases of ulcer There were 3 cases (13.0%) in jejunum, 16 cases (69.6%) in empty and ileum and 4 cases (17.4%) in ileum only. Ileocecal pass rate 70.7% (29/41), 3 cases of asymptomatic retention of capsules, 1 case removed under colonoscopy, the other two were discharged at 26 d and 53 d. Conclusion In patients with eCD and sCD, capsule endoscopy can be used as a safe and effective method for the examination of CD in small intestine, which has a high diagnostic value for judging the extent and range of CD mucosal damage in small intestine.