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目的总结分析腹部恶性纤维组织细胞瘤(MHF)的外科治疗策略及预后相关因素。方法回顾性分析1980年7月至2003年11月间51例腹部恶性纤维组织细胞瘤患者的临床资料。结果术后48例患者获得随访,随访时间为24-304个月,35例患者复发、转移,术后单纯局部复发 15例(29．4％),出现肺及胸膜转移8例(15．7％)、肝转移4例(7．8％)、骨转移6例(11．7％)、肾脏转移2例(3．9％),复发合并转移7例(13．7％)。术后1、3、5年无瘤生存率分别为70．6％、43．1％和 29．4％,累计生存率分别为74．5％、52．9％和31．4％。结论腹部恶性纤维组织细胞瘤侵袭性强, 复发率高,病理分级差,手术完整切除、术后辅以放疗有助于提高患者的远期生存率。
Objective To summarize the surgical treatment strategies and prognostic factors of malignant fibrous histiocytoma (MHF) in the abdomen. Methods The clinical data of 51 patients with malignant fibrous histiocytoma of the abdomen from July 1980 to November 2003 were analyzed retrospectively. Results After the operation, 48 patients were followed up for 24-304 months. 35 patients recurred and metastasized. Only local recurrence occurred in 15 patients (29.4%), and pulmonary and pleural metastasis occurred in 8 patients (15.7 , Liver metastases in 4 cases (7.8%), bone metastases in 6 cases (11.7%), renal metastases in 2 cases (3.9%) and recurrence and metastasis in 7 cases (13.7%). The 1, 3 and 5-year disease-free survival rates were 70.6%, 43.1% and 29.4%, respectively, with cumulative survival rates of 74.5%, 52.9% and 31.4%, respectively. Conclusions Abdominal malignant fibrous histiocytoma has strong invasiveness, high recurrence rate, poor pathological grade, complete resection of the operation and postoperative radiotherapy to improve the long-term survival rate of the patients.