论文部分内容阅读
微/纳米马达是近年来发展的一种可自主运动的新型微/纳米材料,它制备简单、形态多样、可批量化生产,已逐渐应用于生物样品分析及药物运输等领域。由于生物样品成分复杂,传统检测常常需要多步清洗和分离,操作繁琐、耗时较长。微/纳米马达具有自主运动的特性,通过表面生物功能化,可制备成动态的微型生物传感器,实现多种生物分子如核酸、蛋白质、糖蛋白等的实时、快速和灵敏检测。本文总结了近几年微/纳米马达的发展及其在生物传感中的应用,并展望了其在生物分析中的应用前景。
Micro / nano motor is a kind of new micro / nano material that can develop independently in recent years. It has many advantages, such as easy preparation, diverse shape and mass production. It has been gradually applied to biological sample analysis and drug transportation. Due to the complexity of biological samples, traditional testing often requires multiple steps of washing and separating, which is tedious and time consuming. The micro / nano motor has the characteristic of autonomous movement. Through the surface bio-functionalization, it can be used as a dynamic micro-biosensor to realize the real-time, rapid and sensitive detection of various biological molecules such as nucleic acids, proteins and glycoproteins. This paper summarizes the development of micro / nano motor in recent years and its application in bio-sensing and prospects of its application in bioanalysis.