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鉴于硝唑咪的体内代谢与药物的某些副作用有关,因而研究该药在人体内的代谢过程有重要意义。本文报道了应用高效液相层析法对4例轻度感染日本血吸虫的菲律宾男性患者口服硝唑咪后的血清药-时曲线和6种代谢产物进行了测定和分析研究。患者一
In view of the internal metabolism of nitazoxanide and some side effects of drugs, and therefore the study of the drug metabolism in the human body is of great significance. This paper reports the determination of serotonin-time curve and six metabolites of four male Filipina patients with mild infection of Schistosoma japonicum after oral administration of nitazoxan by high performance liquid chromatography (HPLC). Patient one