Kv1.3 channel blockade enhances the phagocytic function of RAW264.7 macrophages

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：liuling

【摘要】

：

This study aimed to comprehend the largely unknown role of voltage-gated potassium channel 1.3(Kv1.3) in the phagocytic function of macrophages. We found that b

【作者】

：

ZHU Hong YAN Li GU JingLi HAO

【机构】

：

DepartmentofPhysiology,SchoolofBasicMedicinePeking,DepartmentofPathophysiology

【出处】

：

中国科学：生命科学英文版

【发表日期】

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2015年9期

【关键词】

：

巨噬细胞吞噬功能钾通道 KVL RAW264.7细胞异硫氰酸荧光素细胞松弛素D LPS Kv1.3 channel phagocytosis macro

【基金项目】

：

supported by the National Key Basic Research Program of China(2011CB93350),National Natural Science Foundation of China(31171088,31471126,81470540,81300139)

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This study aimed to comprehend the largely unknown role of voltage-gated potassium channel 1.3(Kv1.3) in the phagocytic function of macrophages. We found that blocking of the Kv1.3 channel with 100 pmol L-1 Stichodactyla helianthus neurotoxin(Sh K) enhanc

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Kv1.3 channel blockade enhances the phagocytic function of RAW264.7 macrophages

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