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疟疾的复发机理,关系着疟疾的治疗和预防,特别是对间日疟关系极大。因此,这方面的探索一向未曾间断过。Bignami等(1910)提出疟疾复发是由红细胞内期疟原虫所致,但Cooper等(1950)将间日疟隐性阶段的大量血液转种于易感者并不产生感染,而给血者此后又出现复发。Shortt和Garnham(1948)根据在接种食蟹猴疟原虫(plasmodium cynomolgi)子孢子后102天的恒河猴肝细胞内发现了潜隐性裂殖体,认为它是继发性红
The relapse mechanism of malaria is related to the treatment and prevention of malaria, especially the malaria malaria. Therefore, this aspect of exploration has never been interrupted. Bignami et al. (1910) suggested that the relapse of malaria was caused by Plasmodium erythrocytic stages, but Cooper et al. (1950) transplanted large volumes of blood from the recessive phase of vivax to susceptible individuals without causing infection, Recurrence occurs again. Shortt and Garnham (1948) found a cryptosporidium from rhesus monkey hepatocytes 102 days after inoculation with sporozoites of Plasmodium cynomolgi and considered it secondary red