目的:探讨大动脉炎合并神经系统症状的临床特点及预后情况。方法:回顾性分析我院2002-01至2013-10住院的大动脉炎合并神经系统症状274例患者临床特点、影像学资料及预后情况。结果:男女比例1:4.3,平均发病年龄(28.2±11.2)岁,最常见神经系统表现为头晕214例(78.1%),最常见的分型为Ⅲ型(广泛型)112例(40.9%),最常受累动脉为左锁骨下动脉147例(53.6%)。累及3~4支弓上动脉的患者77例(28.1%)。脑卒中患者中,缺血性卒中多见于锁骨下动脉及颈总动脉狭窄闭塞性病变,而出血性卒中患者多见于降腹主动脉和(或)肾动脉狭窄闭塞性病变。心力衰竭是最常见死亡原因,也是存活人群中最常见的心血管事件。结论:大动脉炎患者合并神经系统症状有多种表现,并与累及动脉数量及部位相关。 Objective: To investigate the clinical features and prognosis of aortomitis with neurological symptoms. Methods: The clinical features, imaging data and prognosis of 274 patients with aortic arteritis and neurological symptoms admitted to our hospital from January 2002 to October 2013 were retrospectively analyzed. Results: The ratio of male to female was 1: 4.3, the average age of onset was (28.2 ± 11.2) years old. The most common neurological manifestations were dizzy in 214 cases (78.1%) and the most common type was type Ⅲ (extensive type) in 112 cases (40.9% 147 cases (53.6%) of the left subclavian artery were the most common affected artery. Totally 77 patients (28.1%) were involved in 3 ~ 4 arch arteries. Stroke patients, ischemic stroke common in subclavian artery and common carotid artery occlusive disease, and more common in patients with hemorrhagic stroke in the lower abdominal aorta and / or renal artery stenosis occlusive disease. Heart failure is the most common cause of death and is the most common cardiovascular event among survivors. Conclusion: Patients with arteritis have multiple manifestations of neurological symptoms, which are related to the number and location of arteries involved.