Wave equation migration is often applied to solve seismic imaging problems. Usually, the finite difference method is used to obtain the numerical solution of the wave equation. In this paper, the arbitrary difference precise integration (ADPI) method is discussed and applied in seismic migration. The ADPI method has its own distinctive idea. When dispersing coordinates in the space domain, it employs a relatively unrestrained form instead of the one used by the conventional finite difference method. Moreover, in the time domain it adopts the sub domain precise integration method. As a result, it not only takes the merits of high precision and narrow bandwidth, but also can process various boundary conditions and describe the feature of an inhomogeneous medium better. Numerical results show the benefit of the presented algorithm using the ADPI method. Usually, the finite difference method is used to obtain the numerical solution of the wave equation. In this paper, the arbitrary difference precise integration (ADPI) method is discussed and applied in seismic migration. . The dilution factor in the space domain, it makes a relatively unrestrained form instead of the one used by the conventional finite difference method. Moreover, in the time domain it it adopts the sub domain precise integration method . As a result, it not only takes the merits of high precision and narrow bandwidth, but also can process various boundary conditions and describe the feature of an inhomogeneous medium better. Numerical results show the benefit of the presented algorithm using the ADPI method.