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为探讨单纯疱疹性角膜炎中药治疗前后外周血T细胞亚群变化,用OKT单克隆抗体检测了112例单纯疱疹性角膜炎,随机分为中药治疗组60例,西药对照组52例。发现中药治疗组治愈率86.6%,总有效率98.33%;西药对照组治愈率71.15%,总有效率90.38%;两组差异有显著性(P<0.05)。外周血T细胞亚群:治疗前,两组患者辅助性T细胞(TH)的比例明显低于抑制性T细胞(TS)(P<0.01);中药治疗组辅助性T细胞(TH)治疗后较治疗前明显提高(P<0.05),而西药对照组治疗后辅助性T细胞(TH)较治疗前虽有提高,但差异无显著意义(P>0.1)。说明单纯疱疹性角膜炎患者服中药后,机体内辅助性T细胞比值增加,细胞免疫功能增强。
In order to investigate the change of T lymphocyte subsets in peripheral blood before and after the treatment of herpes simplex keratitis, 112 cases of herpes simplex keratitis were detected by OKT monoclonal antibody and randomly divided into two groups: 60 cases in traditional Chinese medicine group and 52 cases in western medicine group. Found that the cure rate of Chinese medicine treatment group was 86.6%, the total effective rate was 98.33%; western medicine control group cure rate was 71.15%, the total effective rate was 90.38%; there was significant difference between the two groups (P <0.05) . Peripheral blood T lymphocyte subsets: Before treatment, the proportion of helper T cells (TH) in both groups was significantly lower than that of the inhibitory T cells (TS) (P <0.01) (P <0.05). However, the level of T helper (TH) in western medicine group was higher than that before treatment, but the difference was not significant (P> 0.05). The results showed that after the patients with herpes simplex keratitis were treated with traditional Chinese medicine, the ratio of helper T cells in the body increased and the cellular immune function was enhanced.