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社区获得性肺炎(CAP)在发达国家和发展中国家都有相当高的发病率和病死率。虽然对该病的最佳治疗方法进行过研究,但如何治疗各例CAP患者仍有很大差异。已完成的一项研究评价了使用临床路径(住院指南、口服左氧氟沙星或头孢呋辛酯加阿奇霉素标准治疗法、氧气治疗和出院规则)对CAP的治疗结果。该研究涉及7个医疗中心,共7734名患者,其中55%为门诊治疗患者,其余为住院治疗患者。此研究中总体病死率为8%。根据肺炎严重度的危险等级评价肺炎患者的严重程度与早期病死率(入院5d以内)和晚期病死率(入院5d以上)的关系。临床路径的使用与降低早期病死率的关系。并与使用其他抗生素比较,左氧氟沙星单独使用或与头孢呋辛酯加阿奇霉素联用与降低病死率的关系。
Community-acquired pneumonia (CAP) has a very high morbidity and mortality in both developed and developing countries. Although the best treatment for the disease has been studied, how to treat each case of CAP patients are still very different. A completed study evaluated CAP outcomes using clinical pathways (hospital guidelines, oral levofloxacin or cefuroxime axetil standard treatment, oxygen therapy and discharge rules). The study involved seven medical centers with a total of 7734 patients, of whom 55% were outpatient and the rest hospitalized. Overall mortality in this study was 8%. The severity of pneumonia was evaluated according to the severity of pneumonia and the relationship between the severity of the disease and the early mortality (less than 5 days after admission) and the late mortality (more than 5 days after admission). The relationship between the use of clinical pathways and the reduction of early mortality. And with other antibiotics, levofloxacin alone or with cefuroxime axetil combined with azithromycin and reduce mortality.